COMPARATIVE EVALUATION OF THE RESULTS OF APPLYING THE BASIC METHODS OF SURGICAL TREATMENT FOR COLORECTAL CANCER
Keywords:
Laparoscopic surgery, open surgery, colorectal cancerAbstract
In this study, the authors presented an assessment of the comparative effectiveness of laparoscopic surgery and open surgery in the treatment of colorectal cancer. 92 patients with histologically verified colorectal cancer were included in this study. By randomization, patients were divided into a control group (open surgery, n = 46 cases) and a study group (laparoscopic surgery, n = 46 cases). The duration of the operation (122.54 ± 14.85) min and the length of the incision (4.51 ± 1.065) cm were shorter in the study group compared to the control group. Intraoperative blood loss in the main group was (161.12 ± 10.694) ml, versus the control group (218.53 ± 15.369) ml (p<0.05). Patients in the main group had a higher five-year survival rate and a lower incidence of postoperative complications compared to the control group (all P >< 0.05). Therefore, the use of laparoscopic surgery in the treatment of colorectal cancer has better clinical effect than open surgery and is worthy of clinical application.
References
Ahiko, Y., Shida, D., Horie, T., Tanabe, T., Takamizawa, Y., Sakamoto, R., Moritani, K., Tsukamoto, S., & Kanemitsu, Y. (2019). Controlling nutritional status (CONUT) score as a preoperative risk assessment index for older patients with colorectal cancer. BMC Cancer, 19(1), 946. http://dx.doi.org/10.1186/s12885-019-6218-8. PMid:31690275.
Balthazar, C. F., Moura, N. A., Romualdo, G. R., Rocha, R. S., Pimentel, T. C., Esmerino, E. A., Freitas, M. Q., Santillo, A., Silva, M. C., Barbisan, L. F., Cruz, A. G., & Albenzio, M. (2021). Synbiotic sheep milk ice cream reduces chemically induced mouse colon carcinogenesis. Journal of Dairy Science, 104(7), 7406-7414. http:// dx.doi.org/10.3168/jds.2020-19979. PMid:33934866.
Bekaii-Saab T. (2018). How I treat metastatic colorectal cancer. Clinical advances in hematology & oncology: H&O, 18(9), 2-6.
Bell, S., Kong, J. C., Carne, P. W G., Chin, M., Simpson, P., Farmer, C., & Warrier, S. K. (2019). Oncological safety of laparoscopic versus open colorectal cancer surgery in obesity: a systematic review and meta-analysis. ANZ Journal of Surgery, 89(12), 1549-1555. http:// dx.doi.org/10.1111/ans.15081. PMid:30989792.
Bellio, G., Troian, M., Pasquali, A., & Manzini, N. (2019). Outcomes of laparoscopic surgery for pT3/pT4 colorectal cancer in young vs. old patients. Minerva Chirurgica, 74(4), 297-303. http://dx.doi. org/10.23736/S0026-4733.19.07895-7. PMid:30761829.
Chen, C. F., Lin, Y. C., Tsai, H. L., Huang, C. W, Yeh, Y. S., Ma, C. J., Lu, C. Y., Hu, H. M., Shih, H. Y., Shih, Y. L., Sun, L. C., Chiu, H. C., & Wang, J. Y. (2018a). Short- and long-term outcomes of laparoscopic-assisted surgery, mini-laparotomy and conventional laparotomy in patients with Stage I-III colorectal cancer. Journal of Minimal Access Surgery, 14(4), 321-334. http://dx.doi.org/10.4103/ jmas.JMAS_155_17. PMid:29483373.
Chen, L., Gao, H., Liang, J., Qiao, J., Duan, J., Shi, H., Zhen, T., Li, H., Zhang, F., Zhu, Z., & Han, A. (2018b). miR-203a-3p promotes colorectal cancer proliferation and migration by targeting PDE4D. American Journal of Cancer Research, 8(12), 2387-2401. PMid:30662799. Chiu, C. C., Lin, W L., Shi, H. Y., Huang, C. C., Chen, J. J., Su, S. B., Lai, C. C., Chao, C. M., Tsao, C. J., Chen, S. H., & Wang, J. J. (2019). Comparison of oncologic outcomes in laparoscopic versus open surgery for non-metastatic colorectal cancer: personal experience in a single institution. Journal of Clinical Medicine, 8(6), 875. http:// dx.doi.org/10.3390/jcm8060875. PMid:31248135.
Cui, X., Shen, W, Wang, G., Huang, Z., Wen, D., Yang, Y., Liu, Y., & Cui, L. (2018). Ring finger protein 152 inhibits colorectal cancer cell growth and is a novel prognostic biomarker. American Journal of Translational Research, 10(11), 3701-3712. PMid:30662620.
Digiacomo, N., Bolzacchini, E., Veronesi, G., Cerutti, R., Sahnane, N., Pinotti, G., Bregni, M., Artale, S., Verusio, C., Crivelli, F., Capella, C., Sessa, F., & Furlan, D. (2019). Neuroendocrine differentiation, microsatellite instability, and tumor-infiltrating lymphocytes in advanced colorectal cancer with BRAF mutation. Clinical Colorectal Cancer, 18(2), e251-e260. http://dx.doi.org/10.1016/j.clcc.2018.12.003. PMid:30638691.
Fahim, M., Visser, R. A., Dijksman, L. M., Biesma, D. H., Noordzij, P. G., & Smits, A. B. (2019). Routine postoperative ICU admission after colorectal cancer surgery for the elderly patient reduces postoperative morbidity and mortality. Colorectal Disease, 22(4), 408-415.
Gachpazan, M., Kashani, H., Hassanian, S. M., Khazaei, M., Khorrami, S., Ferns, G. A., & Avan, A. (2019). Therapeutic potential of targeting transforming growth factor beta in colorectal cancer: rational and progress. Current Pharmaceutical Design, 25(38), 4085-4089. http:// dx.doi.org/10.2174/1381612825666191105114539. PMid:31692434.
Gaspar-Pintiliescu, A., Oancea, A., Cotarlet, M., Vasile, A. M., Bahrim, G. E., Shaposhnikov, S., Craciunescu, O., & Oprita, E. I. (2020). Angiotensin-converting enzyme inhibition, antioxidant activity and cytotoxicity of bioactive peptides from fermented bovine colostrum. International Journal of Dairy Technology, 73(1), 108-116. http:// dx.doi.org/10.1111/1471-0307.12659.
Hamabe, A., Ogino, T., Tanida, T., Noura, S., Morita, S., & Dono, K. (2019). Indocyanine green fluorescence-guided laparoscopic surgery, with omental appendices as fluorescent markers for colorectal cancer resection: a pilot study. Surgical Endoscopy, 33(2), 669-678. http:// dx.doi.org/10.1007/s00464-018-6504-6. PMid:30341652.
Igder, S., Mohammadiasl, J., Azadpour, S., Mansouri, E., Ashktorab, H., & Mokarram, P. (2020). KRAS mutation and abnormal expression of Cripto-1 as two potential candidate biomarkers for detection of colorectal cancer development. Journal of Cellular Biochemistry, 121(4), 2901-2908. PMid:31692030.
Iwamoto, K., Takahashi, H., Fujii, M., Haraguchi, N., Hata, T., Matsuda, C., Yamamoto, H., Mizushima, T., Mori, M., & Doki, Y. (2019). Correction to: safety of single-site laparoscopic surgery requiring perioperative heparinization in colorectal cancer: propensity score- matched analysis. Annals of Surgical Oncology, 26(Suppl. 3), 892. http://dx.doi.org/10.1245/s10434-019-07839-1. PMid:31531795.
Jouki, M., Rabbani, M., & Shakouri, M. J. (2020). Effects of pectin and tomato paste as a natural antioxidant on inhibition oflipid oxidation and production of functional chicken breast sausage. Food Science Technology, 40(Suppl. 2), 521-527. http://dx.doi.org/10.1590/fst.26419.
Kim, Y. W, & Kim, I. Y. (2017). Comparison of the short-term outcomes of laparoscopic and open resections for colorectal cancer in patients with a history of prior median laparotomy. The Indian Journal of Surgery, 79(6), 527-533. http://dx.doi.org/10.1007/s12262-016- 1520-z. PMid:29217904.
Kojima, Y., Sakamoto, K., & Okuzawa, A. (2019). Experience of using a spray-type anti-adhesion barrier in laparoscopic surgery for colorectal cancer. Journal of Surgical Case Reports, 2019(3), rjz085. http://dx.doi.org/10.1093/jscr/rjz085. PMid:30949335.
Holte K, Nielsen KG, Madsen JL, Kehlet H. Physiologic effects of bowel preparation. Dis Colon Rectum 2004; 47: 1397–402.
Mekic, M. S., Pedisic, I., Sobat, H., Boras, V V, Kirac, I., Stefancic, L., Sekerija, M., Vrdoljak, B., & Vrdoljak, D. V. (2018). The role of complete blood count parameters in patients with colorectal cancer. Acta Clinica Croatica, 57(4), 624-629. http://dx.doi.org/10.20471/ acc.2018.57.04.03. PMid:31168198.
Mostafa, H. S., Ali, M. R., & Mohamed, R. M. (2021). Production of a novel probiotic date juice with anti-proliferative activity against Hep-2 cancer cells. Food Science Technology, 41(Suppl. 1), 105-115. http://dx.doi.org/10.1590/fst.09920.
Pei, J. P., Zhang, C. D., Fan, Y. C., & Dai, D. Q. (2019). Comparison of different lymph node staging systems in patients with resectable colorectal cancer. Frontiers in Oncology, 8, 671. http://dx.doi. org/10.3389/fonc.2018.00671. PMid:30697530.
Van der Pas, M.H. Colorectal cancer Laparoscopic or Open Resection II (COLOR II) study group. Laparoscopic versus open surgery for rectal cancer (COLOR II) short-term outcomes of a randomised, phase 3 trial / M.H. Van der Pas, E. Haglind, M.A. Cuesta, A. Fürst et al. Lancet Oncol. 2013;14:210 - 218.
Tursunova N. I., Valijonova S.A., Valijonov A.F. Analysis of the role of the brca1 and brca 2 genes as a predictor of breast cancer. Prevalence of breast cancer in the republic of uzbekistan. – 2023.
Kurbankulov, U. M., Norbekova, M. X., Valijonova, S.A., & Valijonov, A.F. (2023). Study of morphological and clinical bases of organpreserving surgery for ampular cancer of the rectum.
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