PARKINSON'S DISEASE (CLINIC, DIAGNOSIS, PRINCIPLES OF MODERN TREATMENT)

Abstract

PC is the second most prevalent among neurodegenerative diseases. 1% of the population over the age of 65 suffers from this disease. We can observe a rejuvenation of the disease in the coming decades. The role of several factors in the pathogenesis of the disease is being studied, including hereditary, sexual, age-related factors, metabolic factors and environmental factors affecting the organism. Parkinson's disease has long been considered an "extrapyramidal" disease of the musculoskeletal system. However, at present, much attention is paid to its symptoms. Parkinson's disease begins slowly, unnoticed and progresses to the level of severe disability. The main symptoms of movement are tremor at rest, slowing and slowing of movements, stiffness and loss of postural reflexes. Nonmator symptoms include autonomic symptoms, sleep disturbances, loss of sense of smell, depression and pain. The effective treatments currently offered are pharmacological (dopaminergic drugs, MAO inhibitors, dopamine agonists and amantadine sulfate), operative (apomorphine-pump, duodopa and deep brain stimulation (DBS)) and physical (a set of exercises used for Parkinson's patients). In the surgical treatment of DBS, great attention is paid and good prospects are expected.