DETERMINATION OF LEPTIN LEVEL WITH OTHER BIOCHEMICAL PARAMETERS IN TYPE 2 DIABETIC PATIENTS
Keywords:
Leptin, T2DM, sandwich-based, ELISAAbstract
An adipokine called leptin has been linked to pathways that affect the risk of diabetes mellitus and cardiovascular disease
References
American Diabetes Association. (2012). Diagnosis and classification of diabetes mellitus. Diabetes Care, 35 Suppl 1(Supplement_1), S64-71. doi:10.2337/dc12-s064
Shi, Y., & Hu, F. B. (2014). The global implications of diabetes and cancer. Lancet, 383(9933), 1947–1948. doi:10.1016/S0140-6736(14)60886-2
Hu, F. B. (2003). Sedentary lifestyle and risk of obesity and type 2 diabetes. Lipids, 38(2), 103–108. doi:10.1007/s11745-003-1038-4
Das, P., Bhattacharjee, D., Bandyopadhyay, S. K., Bhattacharya, G., & Singh, R. (2013). Association of obesity and leptin with insulin resistance in type 2 diabetes mellitus in Indian population. Indian Journal of Physiology and Pharmacology, 57(1), 45–50.
Chen, G.-C., Qin, L.-Q., & Ye, J.-K. (2014). Leptin levels and risk of type 2 diabetes: gender-specific meta-analysis: Meta-analysis of leptin and type 2 diabetes. Obesity Reviews: An Official Journal of the International Association for the Study of Obesity, 15(2), 134–142. doi:10.1111/obr.12088
Marita, A. R., Sarkar, J. A., & Rane, S. (2005). Type 2 diabetes in non-obese Indian subjects is associated with reduced leptin levels: study from Mumbai, Western India. Molecular and Cellular Biochemistry, 275(1–2), 143–151. doi:10.1007/s11010-005-1204-7
Buyukbese, M. A., Cetinkaya, A., Kocabas, R., Guven, A., & Tarakcioglu, M. (2004). Leptin levels in obese women with and without type 2 diabetes mellitus. Mediators of Inflammation, 13(5–6), 321–325. doi:10.1080/09629350400008828
Minokoshi, Y., Kim, Y.-B., Peroni, O. D., Fryer, L. G. D., Müller, C., Carling, D., & Kahn, B. B. (2002). Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature, 415(6869), 339–343. doi:10.1038/415339a
Grinspoon, S., Gulick, T., Askari, H., Landt, M., Lee, K., Anderson, E., … Klibanski, A. (1996). Serum leptin levels in women with anorexia nervosa. The Journal of Clinical Endocrinology and Metabolism, 81(11), 3861–3863. doi:10.1210/jcem.81.11.8923829.
Ahima, R. S., & Flier, J. S. (2000). Leptin. Annual Review of Physiology, 62(1), 413–437. doi:10.1146/annurev.physiol.62.1.413
Spiegel K, Tasali E, Penew P, Cauter EV (2004) Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite. Annals of Internal Medicine 141: 846-850. doi.org/10.1016/s0084-3741(08)70348-2
Taheri, S., Lin, L., Austin, D., Young, T., & Mignot, E. (2004). Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Medicine, 1(3), e62. doi.org/10.1371/journal.pmed.0010062
Fadhil, J., Ammar, G., & Tariq, H. (2002). Effects of Type-2 Diabetes Mellitus on Serum Leptin, Insulin, Interlukin-8, and Lipid Profile. Karbala J. Med, 4(1).
Facey, A., Dilworth, L., & Irving, R. (2017). A review of the Leptin hormone and the association with obesity and diabetes mellitus. Journal of Diabetes & Metabolism, 08(03). doi.org/10.4172/2155-6156.1000727
Ahima, R. S., Prabakaran, D., Mantzoros, C., Qu, D., Lowell, B., Maratos-Flier, E., & Flier, J. S. (1996). Role of leptin in the neuroendocrine response to fasting. Nature, 382(6588), 250–252. doi.org/10.1038/382250a0
Myers, M. G., Jr, Leibel, R. L., Seeley, R. J., & Schwartz, M. W. (2010). Obesity and leptin resistance: distinguishing cause from effect. Trends in Endocrinology and Metabolism: TEM, 21(11), 643–651. https://doi.org/10.1016/j.tem.2010.08.002
Enriori, P. J., Evans, A. E., Sinnayah, P., Jobst, E. E., Tonelli-Lemos, L., Billes, S. K., Glavas, M. M., Grayson, B. E., Perello, M., Nillni, E. A., Grove, K. L., & Cowley, M. A. (2007). Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons. Cell Metabolism, 5(3), 181–194. doi.org/10.1016/j.cmet.2007.02.004
Lalrindiki, C., Chanchal, L., Shaini, L., Balary, N., Saishyam, S., Dr Wahengbam, D., & Ng, T. (2019). Evaluation of Plasma Leptin in Type 2 Diabetes Mellitus, IOSR journal. 18, 31–35.
Najam, S. S., Awan, F. R., & Baig, S. M. (2014). Serum adiponectin levels in diabetes, obesity and gender in Punjabi subjects from Faisalabad, Pakistan. JPMA. The Journal of the Pakistan Medical Association, 64(10), 1186–1188.
Gu, X., Chen, Z., & El Bayoumy, I. (2014). Serum leptin levels in obese women with and without type 2 diabetes mellitus. Minerva Endocrinologica, 39(3), 223–229.
Liu, W., Zhou, X., Li, Y., Zhang, S., Cai, X., Zhang, R., … Ji, L. (2020). Serum leptin, resistin, and adiponectin levels in obese and non-obese patients with newly diagnosed type 2 diabetes mellitus: A population-based study: A population-based study. Medicine, 99(6), e19052. doi:10.1097/MD.0000000000019052
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