CLINICAL USES OF PREBIOTICS AND RULE OF PROBIOTICS INFANT FORMULA IN TREATMENT OF ACUTE DIARRHEA (PROSPECTIVE STUDY)
Keywords:
microbiome, modifying formula, rotavirus infectionAbstract
Probiotics are defined as "live microorganisms" that are part of a healthy gut microbiota and have been shown to help treat a variety of gastrointestinal diseases in kids, including acute gastroenteritis. The purpose of this review is to assess the pathogen-specific function of Supplemental probiotic use for treating diarrhea in young children. Studies looking into the effects of probiotics and synbiotics on the outcome of acute gastroenteritis with a known etiology were identified through a search of scholarly databases. There were 32 studies found; most looked at probiotics and their effect on rotavirus gastroenteritis, whereas only a few looked at probiotics and bacterial diarrhea separately. The most studied strains, including Lactobacillus rhamnosus (L. rhamnosus), Lactobacillus reuteri, and Saccharomyces boulardii, have been shown to reduce diarrhea and hospitalization time, particularly in the presence of rotavirus infection. Equally effective, and perhaps more influential on rotavirus fecal shedding, were combined preparations comprising at least one of the aforementioned strains. It has also been suggested that rotavirus immunization status is a major determining element of the effect of probiotic use. More research is needed, and larger cohort studies are necessary, because there is a dearth of studies examining bacterial etiologies and clinical trials conducted in ambulatory care units.methods . The total was 300 child from 20 of september 2020 to 20 of September 2022 . prospective study . Conclusio Infants with a more developed immune system, like those at five months or older, can benefit from prebiotics in their formula, and this is something that the supports.Aim Interest in probiotics continues to rise, sparked by new findings about the importance of the gut microbiota to human health. Focusing on children, the authors intended to summarize the current state of knowledge about probiotics.
References
Bernaola Aponte, G.; Bada Mancilla, C.A.; Carreazo, N.Y.; Rojas Galarza, R.A. Probiotics for Treating Persistent Diarrhoea in
Children. Cochrane Database Syst. Rev. 2013, 2013, CD007401. [CrossRef] [PubMed]
Thomas, D.W.; Greer, F.R.; American Academy of Pediatrics Committee on Nutrition; American Academy of Pediatrics Section on
Gastroenterology, Hepatology and Nutrition. Probiotics and Prebiotics in Pediatrics. Pediatrics 2010, 126, 1217–1231. [CrossRef][PubMed]
Kechagia, M.; Basoulis, D.; Konstantopoulou, S.; Dimitriadi, D.; Gyftopoulou, K.; Skarmoutsou, N.; Fakiri, E.M. Health Benefits of
Probiotics: A Review. ISRN Nutr. 2013, 2013, 481651. [CrossRef] [PubMed]
Tissier, H. Traitement des Infections Intestinales par la Méthode de Transformation de la Flore Bactérienne de l’Intestin. Compt.Rend. Soc. Biol. 1906, 60, 359–361.
Salminen, S.J.; Gueimonde, M.; Isolauri, E. Probiotics That Modify Disease Risk. J. Nutr. 2005, 135, 1294–1298. [CrossRef][PubMed].
Review Pathogen-Specific Benefits of Probiotic and Synbiotic Use in Childhood Acute Gastroenteritis: An Updated Review of the Literature Maria Oana Sasaran 1 , Cristina Oana Marginean 2,* , Heidrun Adumitrachioaiei 3 and Lorena Elena Melit,
Clinical Effects of Prebiotics in Pediatric Population ROK OREL AND LEA VODUŠEK REBERŠAKFrom University Medical Centre, Ljubljana, University Children’s Hospital; Ljubljana, Slovenia.
Correspondence to: Prof Rok Orel, University Children’s Hospital, BohoriÃceva 20, 1000 Ljubljana, Slovenia. rok.orel@kclj.si
Agostoni C, Axelsson I, Braegger C, et al. Probiotic bacteria in dietetic products for infants: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2004;38(4):365-374.
Boehm G, Moro G. Structural and functional aspects of prebiotics used in infant nutrition. J Nutr. 2008;138(9):1818S-1828S.
Veereman-Wauters G. Application of prebiotics in infant foods. Br J Nutr.
;93(Suppl 1):S57-S60.
Parracho H, McCartney AL, Gibson GR. Probiotics and prebiotics in infant nutrition. Proc Nutr Soc. 2007;66(3):405-411.
Thomas DW, Greer FR, American Academy of Pediatrics Committee on Nutrition, American Academy of Pediatrics Section on Gastroenterology, Hepatology, and Nutrition. Probiotics and prebiotics in pediatrics. Pediatrics.2010;126(6):1217-1231.
Rao S, Srinivasjois R, Patole S. Prebiotic supplementation in full-term neonates: a systematic review of randomized controlled trials. Arch Pediatr Adolesc Med.2009;163(8):755-764.
Saavedra JM. Use of probiotics in pediatrics: rationale, mechanisms of action, and practical aspects. Nutr Clin Pract. 2007;22(3):351-365.
Srinivasjois R, Rao S, Patole S. Prebiotic supplementation of formula in pretermneonates: a systematic review and meta-analysis of randomised controlled trials. Clin Nutr. 2009;28(3):237-242.
Chouraqui J, Grathwohl D, Labaune J, et al. Assessment of the safety, tolerance, and protective effect against diarrhea of infant formulas containing mixtures of probiotics or probiotics and prebiotics in a randomized controlled trial. Am J ClinNutr. 2008;87(5):1365-1373.
Arslanoglu S, Moro GE, Boehm G. Early supplementation of prebiotic oligosaccharides protects formula-fed infants against infections during the first 6 months of life. J Nutr. 2007;137(11):2420-2424.
Braegger C, Chmielewska A, Decsi T, et al. Supplementation of infant formula with probiotics and/or prebiotics: a systematic review and comment by the ESPGHAN committee on nutrition. J Pediatr Gastroenterol Nutr. 2011;52(2):238-250.
Szajewska H, Mrukowicz JZ. Probiotics in the treatment and prevention of acuteinfectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials. J Pediatr Gastroenterol
Nutr. 2001;33(Suppl 2):S17-S25.
Van Niel CW, Feudtner C, Garrison MM, Christakis DA. Lactobacillus therapy for acute infectious diarrhea in children: a meta-analysis. Pediatrics. 2002;109(4):678-684.
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