DISEASES OF THE SUBTRACTION SYSTEM.
Keywords:
Subtraction system, waste elimination, physiological diseasesAbstract
This article explores diseases of the subtraction system, a hypothetical concept that metaphorically describes the malfunction of essential processes that manage reduction, elimination, or minimization within biological or mechanical systems. Focusing on analogous systems in both human physiology and industrial machinery, the article provides insights into how "subtraction failures"—the inability to effectively remove waste or reduce inputs—can lead to dysfunctions and systemic breakdowns. It examines these processes in fields like nephrology, wastewater treatment, and electrical systems, where failure in subtraction mechanisms can severely impact performance and health.
References
Jobe, A.H. Animal models, learning lessons to prevent and treat neonatal chronic lung disease. Front. Med.
, 2, 49, doi: 10.3389/fmed.2015.00049
Bose, C.; Van Marter, L.J.; Laughon, M.; O’ Shea, T.M.; Allred, E.N.; Karna, P.; Ehrenkranz, R.A.; Boggess,
K.; Leviton, A.; Extremely Low Gestational Age Newborn Study Investigators. Fetal growth restriction and
chronic lung disease among infants born before the 28th week of gestation. Pediatrics 2009, 124, e450– 458
Bhat, R.; Salas, A.A.; Foster, C.; Carlo, W.A.; Ambalavanan, N. Prospective analysis of pulmonary
hypertension in extremely low birth weight infants. Pediatrics 2012, 129, e682– 9
Shegal, A.; Gwini, S.M.; Menahem, S.; Allison, B.J.; Miller, S.L.; Polglase, G.R. Preterm growth restriction and
bronchopulmonary dysplasia: The vascular hypothesis and related physiology. J. Physiol. 2018,
doi:10.1113/JP276040 [Epub ahead of print]
Krishnan, U.; Feinstein, J.; Adatia, I.; Austin, E.D.; Mullen, M.P.; Hopper, R.K.; Hanna, B.; Romer, L.; Keller,
R.L.; Fineman, J.; et al. Evaluation and management of pulmonary hypertension in children with
bronchopulmonary dysplasia. J. Pediatr. 2017, 188, 24– 34
Willfuhr, A.; Brandenberger, C.; Piatkowski, T.; Grothausmann, R.; Nyengaard, J.R.; Ochs, M.; Mühlfeld, C.
Estimation of the number of alveolar capillaries by the Euler number (Euler-Poincare characteristics). Am. J.
Physiol. Lung Cell Mol. Physiol. 2015, 309, L1286– 93
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