EPIDEMIOLOGY OF LIVER CIRRHOSIS AND ASSOCIATED COMPLICATIONS: CURRENT KNOWLEDGE AND FUTURE DIRECTIONS

Authors

  • Tadjibayev Sherzodbek Maxamadjanovich
  • Yusupova Gavxaroy Baxtiyorjon qizi
  • Mamadaliyeva Madina Xojiakbar qizi
  • Akromjonava Xalimaxon O’rmonbek qizi
  • Nabijonova Nazokat Nabijon qizi

Keywords:

TIPS, Xenotransplantation, magnetic resonance elastography

Abstract

Liver cirrhosis is a progressive disease characterized by the irreversible scarring of the liver, leading to its functional impairment. It is a major global health concern due to its high morbidity, mortality, and the economic burden it imposes on healthcare systems. Cirrhosis can result from a variety of etiologies, including chronic viral hepatitis, alcohol use, non-alcoholic fatty liver disease (NAFLD), and autoimmune disorders. Understanding the epidemiology of cirrhosis and its associated complications is crucial for the development of effective preventive and therapeutic strategies. This article will review the current knowledge regarding the epidemiology of liver cirrhosis, the complications associated with it, and future research directions in the field

References

Research papers published in journals like The

Lancet Gastroenterology & Hepatology, Hepatology,

and Journal of Hepatology.

Weinberg EM, Trinh HN, Firpi RJ, Bhamidimarri KR,

Klein S, Durlam J, Watkins S, Reddy KR, Weiss M,

Zink RC, Lok AS. Lean Americans With Nonalcoholic

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and Comorbid Diseases. Clin Gastroenterol

Hepatology 2021; 19: 996-1008.e6

Clinical Guidelines:

Guidelines from reputable medical organizations

like the American Association for the Study of

Liver Diseases (AASLD), the European

Association for the Study of the Liver (EASL),

and the World Health Organization (WHO)

provide insights into best practices in the

management of liver cirrhosis and its

complications.

Leading hepatology textbooks such as Hepatology:

A Textbook of Liver Disease by Michael F. Sorrell or

Liver Disease by James S. Dooley

Institutional Websites:

The websites of institutions such as the National

Institute of Diabetes and Digestive and

Kidney Diseases (NIDDK) and the American

Liver Foundation (ALF) offer educational

resources and updates on liver disease research

and clinical management.

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Published

2025-03-15

How to Cite

Tadjibayev Sherzodbek Maxamadjanovich, Yusupova Gavxaroy Baxtiyorjon qizi, Mamadaliyeva Madina Xojiakbar qizi, Akromjonava Xalimaxon O’rmonbek qizi, & Nabijonova Nazokat Nabijon qizi. (2025). EPIDEMIOLOGY OF LIVER CIRRHOSIS AND ASSOCIATED COMPLICATIONS: CURRENT KNOWLEDGE AND FUTURE DIRECTIONS. World Bulletin of Public Health, 44, 53-60. Retrieved from https://scholarexpress.net/index.php/wbph/article/view/5089

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Section

Articles