CORRELATION BETWEEN HELICOBACTER PYLORI AND TYPE 2 DIABETES IN KIRKUK-IRAQ
Keywords:
Helicobacter pylori, Type 2 diabetes, K1 hospital, KirkukAbstract
Background: Helicobacter pylori is a common bacterial pathogen of human beings, causes different gastric problems as ulcers, tumors and inflammation as gastritis. The chronic inflammation may have impact on glucose and lipid absorption. Diabetes mellitus is characterized by a high level of blood glucose Glycated hemoglobin (HBA1C) The objective of the study is to show the relationship between H. pylori and diabetes mellitus. Methods: The study was conducted on 116 patients with type 2 diabetes mellitus who attended K1 hospital in North Oil Company, Kirkuk, and 80 healthy individuals. H. pylori was detected by using H. pylori antigen rapid test in feces. Estimation of sugar was done by a high level of blood glucose and glycated hemoglobin (HBAIC) using a fully smart automated clinical chemistry analyzer. Results: This study showed the frequency of H. pylori in diabetic patients was 28.4%, the highest rate was among 30-39 years, employees, and illiterates. The lowest was among university-educated level and no cases seen among students. Conclusions: Higher rate of H. pylori among patients with diabetes may indicate a strong link between H. pylori and Type 2 diabetes mellitus
References
Alatbee AHD. High prevalence of Helicobacter pylori in Basra city Southern Iraq. Journal of Physics: L Conference Series, 2019, 1279 012073. 2. Thevenot T, Josenhans C, Brown LM. Helicobacter pylori: epidemiology and routes of transmission. Epidemiol Rev, 2000, 22: 283- 97. 3. Personnet J. Helicobacter pylori and gastric cancer. Gastroentroenterol Clin. North Am. , 1993, 22: 89k-104. 4. Wotherpoon AC, Ortiz-Hidalgo C, Falzon MR, Isaacson PG . Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 1991, 338, 1175-1176. 5. YamaoAC, ka Yoshio. Helicobacter pylori: Molecular Genetics and cellular biology. Caister Academic Personnet J. Helicobacter pylori and gastric cancer. Gastroentroenterol Clin. North Am., 1993, 22: 89-104. 6. Gunji T, Matsuhashi N, Sato H. et al. A Helicobacter pylori infection significantly increases insulin resistance in the asymptomatic Japanese population. Helicobacter, 2009, 14: 144-150. 7. Eshraghian A, Hashemi SA, Hamidian JA, et al. Helicobacter pylori infection as a risk factor for insulin resistance. Dig. Dis. Sci. , 2009, 54: 1966-1970. 8. Imai J, Yamada T, Saito T. et al. Eradication of insulin resistance. Lancet, 2009, 374: 264. 9. Horikawa C, Kodama S, Fujihara K. et al., High risk of failing eradication of Helicobacter pylori in patients with diabetes: A meta-analysis. Diabetes Res. Clin Pract., 2014, 106: 81-87. 10. Wada Y, Hamamoto Y, Kawasaki Y. et al., The eradication of Helicobacter pylori does not affect glycemic control in Japanese subjects with type 2 diabetes. Japn. Clin. Med., 2013, 4: 41-43. 11. Agardh E., Allebeck P., Hallqvist J. et al. Type 2 diabetes incidence and socio-economic position: a systematic review and metaanalysis. Int J. Epidemiol., 2011, 40: 804-818. 12. Perdichizzi G, Bottari M, Pallio S. et al. Gastric infection by Helicobacter pylori and antral gastritis in hyperglycemic obese and in
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.