EFFECT OF AQUEOUS EXTRACT OF CYPERUS ESCULENTUS TUBERS AND DAPAGLIFLOZIN ON THE KIDNEYS IN FEMALE RATS WITH RENAL FAILURE INDUCED BY CARBON TETRACHLORIDE CCL4
Keywords:
Cyperus esculentus, CCl4, kidney function, DapagliflozinAbstract
The study was conducted on 16 female rats at the age of 8 weeks and weighing 200-225 grams were randomly distributed into 4 groups The experiment was designed as follows: The first group included the group of natural standard animals (control) G1, and the second group included the group of animals infected with carbon tetrachloride compound CCL4 that was injected at a dose of 0.1 ml / 100 g of animal weight for 30 days through the proton membrane and byTwo rows per week and left untreated positive control sample G2 and the third group included the group of animals injected with carbon tetrachloride compound ccl4 and was treated with chemical drugs (Dapagliflozin) G3 and the fourth group included the group of animals injected with carbon tetrachloride compound ccl4 It was treated with aqueous extract of Cyperus esculentus tubers
References
Abu Al-Qasim, Iman, Zuhur Al-Balbali, Zahwa Othman, Omar Muhammad Abu Khurais, Ali Faraj Hawado Ibrahim Al-Senussi Al-Mukhtar (2016) Study of the biological effect of aqueous and organic extract of Nigella sativa plant and cress on some types of gram-negative and gram-positive bacteria.Sebha University Journal of Research and Applied Sciences, Volume 15, Issue 1, pp. 1-8 Maher Hamid Salman ((2018) Fundamentals of medicinal plants and theiractive compounds. Al-Qasim Green University - College of Agriculture, Deposit number in the House of Books and Documents in Baghdad.415 Cockcroft, D. W., and Gault, H. (1976). Prediction of creatinine clearance from serum creatinine. Nephron, 16(1), 31-41. El-Hashash, S. A., ElMoslemany, A. M., El-Mageed, A., and Amany A. (2020). Effect of Some Medicinal Plant Seeds on CCl4-Induced Hepatotoxicity in Experimental Rats. Egyptian Journal of Nutrition and Health, 15(1), 101–120.
Harborne, J.B(1984) Phytochemical Methods, A guide to modern techniques of plant analysis. 2nd. ed. Chapman and Hail Ltd. , London .
Mahmod,S.A.A, and Sabry,S.M (2021) Protective Effect of Tiger Nut (Cyperus esculentus L.) on Hypercholesterolemia Rats, Home Econ. J. Vol. (37), No. (2).
Manna, C, Migliardi, V, Sannino, F, DeMartino, A, Capasso, R(2005) Protective effects of synthetic hydroxytyrosol acetyl derivatives against oxidative stress in human cells. J. Agric. Food Chem. 2005; 53: 9602-9607.
Muhammad, R. M (2017). Study of the protective effect of the ethanolic extract of Zingiber officinale on rats treated with carbon tetrachloride.
Nwawuba, S.U, Okechukwu, F.C (2018) The effect of Cyperus esculentus (Tiger nut) oil on liver, kidney and hematological biomarkers in low dose streptozocin and high fat diet exposed male Wistar rats. International Journal of Food Science and Nutrition. 3(4):148-152. 25.
SAS (2012) Statistical Analysis System, User,s Guide. Statistical. Version 9.1th
ed. SAS. Institute Incorporated Cary. N.C. USA
Tietz, N.W(1987) Fundamentals of clinical chemistry. W.B.Saunders Co, Philadelphia, USA. Pp: World Health Organization (2015) World Health Statistics
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