INVESTIGATION ROLE OF VITAMIN D3 AND IMMUNOLOGICAL MARKERS IN PATHOGENESIS OF HASHIMOTO THYROIDITIS
Keywords:
vitamin, IL-38, IL-15, Hashimoto thyroiditisAbstract
Background; The primary reason of hypothyroidism is Hashimoto's thyroiditis (HT), the most common autoimmune illness that causes thyroid cell damage due to lymphocyte invasion. Its distinctive features include an elevated amount of autoantibodies targeting thyroid peroxidase and thyroglobulin. Objective IL-38, IL-15, vitamin D3, anti-TPO, and anti-TGA characteristics are being studied with the aim of determining their role in the etiology of Hashimoto's thyroid disorders (HT).
References
Admoni, O., Rath, S., Almagor, T., Elias-Assad,
G., & Tenenbaum-Rakover, Y. (2020). Longterm follow-up and outcomes of autoimmune
thyroiditis in childhood. Frontiers in
endocrinology, 11, 309.
Admoni, O., Rath, S., Almagor, T., Elias-Assad,
G., & Tenenbaum-Rakover, Y. (2020). Longterm follow-up and outcomes of autoimmune
thyroiditis in childhood. Frontiers in
endocrinology, 11, 309.
Ajjan, R. A., & Weetman, A. P. (2015). The
pathogenesis of Hashimoto’s thyroiditis: further
developments in our understanding. Hormone
and Metabolic Research, 47(10), 702-710.
Ajjan, R. A., Watson, P. F., & Weetman, A. P.
(1997). Detection of IL-12, IL-13, and IL-15
messenger ribonucleic acid in the thyroid of
patients with autoimmune thyroid disease. The
Journal of Clinical Endocrinology &
Metabolism, 82(2), 666-669.
Allard-Chamard, H., Mishra, H. K., Nandi, M.,
Mayhue, M., Menendez, A., Ilangumaran, S., &
Ramanathan, S. (2020). Interleukin-15 in
autoimmunity. Cytokine, 136, 155258.
Almsaid, H., & Khalfa, H. M. (2020). The effect
of Ketogenic diet on vitamin D3 and
testosterone hormone in patients with diabetes
mellitus type 2. Current Issues in Pharmacy and
Medical Sciences, 33(4), 202-205.
Altieri, B., Muscogiuri, G., Barrea, L., Mathieu,
C., Vallone, C. V., Mascitelli, L., ... & Della Casa,
S. (2017). Does vitamin D play a role in
autoimmune endocrine disorders? A proof of
concept. Reviews in Endocrine and Metabolic
Disorders, 18, 335-346.
Arakawa, Y., Watanabe, M., Takemura, K.,
Inoue, N., Hidaka, Y., & Iwatani, Y. (2017). The
IL 15+ 96522 A> T functional polymorphism is
related to the differentiation of Th17 cells and
the severity of Hashimoto's
disease. International Journal of
Immunogenetics, 44(2), 41-50.
Bensen, J. T., Dawson, P. A., Mychaleckyj, J. C.,
& Bowden, D. W. (2001). Identification of a
novel human cytokine gene in the interleukin
gene cluster on chromosome 2q12-14. Journal
of Interferon & Cytokine Research, 21(11), 899-
Botelho, I. M. B., Neto, A. M., Silva, C. A.,
Tambascia, M. A., Alegre, S. M., & ZantutWittmann, D. E. (2018). Vitamin D in
Hashimoto’s thyroiditis and its relationship with
thyroid function and inflammatory
status. Endocrine journal, 65(10), 1029-1037.
Bouillon, R., Manousaki, D., Rosen, C.,
Trajanoska, K., Rivadeneira, F., & Richards, J.
B. (2022). The health effects of vitamin D
supplementation: Evidence from human
studies. Nature Reviews Endocrinology, 18(2),
-110.
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