HISTOLOGICAL STUDY OF PANCREAS TISSUE OF ALBINO RATS WHICH THE TREATED WITH FLUTAMIDE

Authors

  • Ameer Jawad Hadi College of biotechnology/Al-Qasim Green University
  • Siham adnan abdulsada Directorate Education Babil
  • Hussein Jasim Alharbi University of Babylon

Keywords:

Flutamide, Pancreas, Rats

References

Apotex Inc. APO-FLUTAMIDE® product monograph. Weston, Ontario; 28 October 2002.

McEvoy GK, editor. AHFS 2006 Drug Information®. Bethesda, Maryland: American Society of Health-System Pharmacists, Inc. p. 1056-1057

Matsuzaki Y, Nagai D, Ichimura E, Goda R, Tomura A, Doi M, et al. Metabolism and hepatic toxicity of flutamide in cytochrome P450 1A2 knockout SV129 mice. J Gastroenterol 2006;41:231-9.

Thole Z, Manso G, Salgueiro E, Revuelta P, Hidalgo A.Hepatotoxicity induced by antiandrogens: a review of the literature. Urol Int 2004;73:289-95.

Boelsterli UA, Ho HK, Zhou S, Leow KY. Bioactivation and hepatotoxicity of nitroaromatic drugs. Curr Drug Metab 2006;7:715-27.

Fau D, Eugene D, Berson A, Letteron P, Fromenty B, Fisch C, et al. Toxicity of the antiandrogen flutamide in isolated rat hepatocytes. J Pharmacol Exp Ther 1994;269:954-62.

Ozono S, Yamaguchi A, Mochizuki H, Kawakami T, Fujimoto K, Otani T, et al. Caffeine test in predicting flutamideinduced hepatic injury in patients with prostate cancer. Prostate Cancer Prostatic Dis 2002;5:128-31.

Kang P, Dalvie D, Smith E, Zhou S, Deese A. Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes. Drug Metabol Dispos 2007;35:1081-8.

Manso G, Thole Z, Salgueiro E, Revuelta P, Hidalgo A.Spontaneous reporting of hepatotoxicity associated with antiandrogens: data from the Spanish pharmacovigilance system. Pharmacoepidemiol Drug Saf 2006;15

Ahmed,O.H.(2018). Histological Effect of Androgenic Anabolic Steroide Dianabol in

Heart and Some Blood Parameters of Male Albino Rats. .J.Global Pharma Tech. 10(03): 215-219

Ahmed,O.H.(2018). EFFECT OF FUMONISIN B1 ON HISTOLOGY OF SPLEEN OF BROILER CHICKEN GALLUS GALLUS. Biochem. Cell. Arch. Vol. 18, No. 2, pp. 1755-1761,

-Ali,H.A &Ahmed,O.H.(2018). Molecular Identification of Entamoeba Histolytica In Amoebiasis Patients.J.Global Pharma Tech. Vol.10 Issue 10 (Suppl.):403-407

Greenway BA. Effect of flutamide on survival in patients with pancreatic cancer: results of a prospective, randomised, double blind, placebo controlled trial. Br Med J 1998; 316:1935-8.

Negi SS, Agarwal A, Chaudhary A. Flutamide in unresectable pancreatic adenocarcinoma: a randomized, double-blind, placebo-controlled trial. Invest New Drugs 2006; 24: 189-94.

Gomez JL, Dupont A, Cusan L, Tremblay M, Suburu R,Lemay M, et al. Incidence of liver toxicity associated with the use of flutamide in prostate cancer patients. Am J Med 1992;92:465-70

Nelson WG, De Marzo AM, Isaacs WB. Prostate cancer. N Engl J Med 2003; 349: 366–81.

Vozianov A, Reznikov A, Klimenko I. Androgen de¬privation strategy in prostate cancer. Naukova Dumka: Kyiv, Ukraine, 2001, 240 p.

Anfal A Sh, Ahmed O H and Wasna A M A (2017) Toxipathological Effect of Silver Nanoparticles on The Brain and liver of Albino Rats. International J. ChemTech Res. Vol.10 No.2, pp 624-629

Shaw J, Mayer A, Corrie P. (2000) Phase II study of flutamide in unresectable pancreatic cancer. Proc. Am. Soc. Clin. Oncol 19: 274a

Louvet C, Andre T, Lledo G, Hammel P, Bleiberg H, Bouleuc C, Gamelin E,Flesch M, Cvitkovic E, de Gramont A (2002) Gemcitabine combined with oxaliplatin in advanced pancreatic adenocarcinoma; final results oof the GERCOR multicenter phae Ii study. J. Clin. Oncol 20: 1512 – 1518

Greenway BA, Iqbal MJ, Johnson PJ, Williams R (1983) Low testosterone concentrations in patients with carcinoma of the pancreas. Br. Med. J 286: 93 – 95

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Published

2023-07-18

How to Cite

Ameer Jawad Hadi, Siham adnan abdulsada, & Hussein Jasim Alharbi. (2023). HISTOLOGICAL STUDY OF PANCREAS TISSUE OF ALBINO RATS WHICH THE TREATED WITH FLUTAMIDE. World Bulletin of Public Health, 24, 53-57. Retrieved from https://scholarexpress.net/index.php/wbph/article/view/3014

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